磷水能否與母奶和配方奶同時服用？真相大揭秘-兒科

裴仁生 醫師回覆-兒科

醫事人員經歷： 衛生福利部桃園醫院 兒科 主治醫師

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您好: 根據資料顯示; 磷水儘量不要和含鈣的食物併用, 以免發生鈣磷沉澱, 影響吸收。
下表中最後一行也是有如是提醒。
健康快樂!
仁生 謹上
Neutral Phosphate
Supply: 每包藥粉含NaH2PO4．H2O 17.5g及Na2HPO4 28g;
每包共含元素磷10g (in 500mL dist water：磷 20 mg / mL)
鈉 38.23g (in 500mL dist water：鈉76.5 mg / mL)
Description: Neutral Phosphate is an agent for oral phosphate supplementation in hypophosphatemia therapy.
Pharmacokinetics: Bioavailibility: ~1% to 20%
Indication: 低磷性佝僂症、補充磷
Dosage and Administration:
Phosphate depletion: oral,
0.5 ~ 1 g elemental phosphorus 2-3 times/day (25 ~50 mL bid~ tid)
Hypophosphatemic rickets: oral,
1 ~ 4 g elemental phosphorus per day in divided doses
Adverse drug reaction: edema, hypotension; dizziness; headache; calcium phosphate precipitation; hypernatremia; hyperphosphatemia; hypocalcemia; abdominal bloating; abdominal pain; diarrhea; mucosal bleeding; nausea; superficial mucosal ulcerations; vomiting; acute renal failure
Contraindications: Contraindicated use in patient with acute colitis, acute phosphate nephropathy (biopsy proven), bowel obstruction, bowel perforation, congenital megacolon, gastric retention, hypomotility syndromes, ileus, pseudo-obstruction, severe chronic constipation, toxic megacolon, unstable angina
Note:1) 每包Neutral Phosphate請以500ml溫開水沖泡溶解; 再依照醫囑劑量及服法服用。
2) 1 mmol phosphate = 31 mg phosphorus; 1 mg phosphorus = 0.031 mmol phosphate
3) 請與antacids、calcium salts 、iron salts、 magnesium salts、Sucralfate、 Bisphosphonate derivatives分開使用以免降低磷的吸收

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回覆日期：2018/04/05
資料來源：台灣e院 - 磷水(Phosphate Oral Solution)是否能和母奶和配方奶一起服用？