新發現的胸部影像學檢查結果:正子攝影和電腦斷層報告-胸腔內科

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正子攝影和電腦斷層報告?


以下是今年3月份剛確診的電腦斷層報告(有打顯影劑)Imaging findings: CT of the Chest: The non-enhanced axial and reformatted images are obtained by MDCT. Irregular poor-enhanced mass lesions (~5.8cm @ Se/Im:7/20) (~4.8cm @ Se/Im:3/56) in the right lower lobe with invasion to the right hilum and mediastinum. There are enlarged lymph nodes in the right hilum and mediastinum. Interstitial thickening and ground glass opacity in the right lower lobe of the lung. There is a cystic lesion without significant enhancement in the right kidney. Small hypodense lesions are noted in the liver.Impression: 1) Suspect bronchogenic carcinoma (~5.8cm @ Se/Im:7/20) (~4.8cm @ Se/Im:3/56) in the right lower lobe with invasion to the right hilum and mediastinum. Differential diagnosis: tuberculosis. 2) Suspect metastatic lymphadenopathy in the right hilum and mediastinum. 3) Suspect lymphangetic carcinomatosis in the right lower lobe of the lung. 4) A right renal cyst, Bosniak Classification category I. 5) Small hepatic cysts. ============<< Uniform Cancer Staging Format for Lung Cancer >>============= TNMStage: T4N2M0 (according to AJCC cancer staging 8th ed., 2016) AJCC prognostic stage group: IIIB ================================================================= 1.Imaging date Date of examination (Y/M/D): 2022/03/22 Imaging modality Imaging byCT scan 2.Tumor Location: (TumorLocation) ■Right lower lobe Tumor Size: (TumorSize) Nodule/lesion feature: ■Solid (Se/Im:7/20) ■Size of solid part: 5.8 cm (greatest dimension) 3.Tumor invasion: (TumorCharacteristics & OtherOrganInvasion) ■Invades hilar fat ■Separate tumor nodule(s) in the same lobe as the primary ■Invades mediastinum or mediastinal fat 4.Regional nodal metastasis: (LymphNode) ■Suspicious nodal metastatic location(s): ■ipsilateral hilar ■ipsilateral mediastinal 5.Distant metastasis: (MetastaticOrgan) ■No distant metastasis以下是6月份電腦斷層報告(沒有打顯影劑)CT of chest without contrast enhancement shows: Techniques: From lower neck to the renal level in 3-mm contiguous section for non-enhanced CT studyCoronal (3mm) and sagittal (5mm) reconstruction performedImaging findings: Some small lymph nodes at left supraclavicular region Regressive change of subpleural consolidation in the upper RLL as compared with last imagesObvious regression of the RLL cavitary lesion Ground glass opacity in the medial RLLInfiltration and atelectasis in the RLLStable 4mm nodule in the LLLRegressive change of the enlarged right hilar and mediastinal LN sas compared with last imagesNo definite pneumothorax or pleural effusion No definite pericardial effusion or pneumopericardium A rightrenal cyst No obvious adrenal mass found No definite enlarged lymph nodes noted in the upper retroperitoneum Some small but visible lymph nodes at the upper retroperitoneum Impression: * Some small lymph nodes at left supraclavicular region * Regressive change of subpleural consolidation in the upper RLLas compared with last images* Obvious regression of the RLL cavitary lesion * Ground glass opacity in the medial RLL* Stable 4mm nodule in the LLL* Regressive change of the enlarged right hilar and mediastinal LN以下是9月份電腦斷層報告(有打顯影劑)Computed Tomography of Chest With and Without Enhancement Shows:Techniques: From lower neck to liver level in 3-mm section for non-contrast CTFrom lower neck to liver level in 3-mm section for contrast CTCoronal (3mm) and sagittal (5mm) reconstructions are also doneThis study has been compared to previous CT study on 20220617Findings:Partial regressive change of subpleural consolidation in the upper RLL as compared with last imagesPartial regressive change of ground glass opacity in the medial RLLStable 4mm nodule in the LLLStable small lymph nodes at left supraclavicular, right hilar and mediastinal regionSome small but visible lymph nodes at the upper retroperitoneum Stable right renal cyst Hypodense lesions without enhancement in right lobe liver, may be cysts No definite pneumothorax.No definite pleural effusion.No definite pericardial effusion.Patent main pulmonary trunk and branches, no obvious thrombus noted.No definite of double lumen, intimal flap or medial displacement of aorta wall suggesting aortic dissection.No definite adrenal mass.No definite hydronephrosis.No definite bone destruction.Kindly note that subtle mucosal lesion could not be well evaluated on routine CTIMP:* Partial regressive change of subpleural consolidation in the upper RLL as compared with last images* Partial regressive change of ground glass opacity in the medial RLL* Stable 4mm nodule in the LLL* Stable small lymph nodes at left supraclavicular, right hilar and mediastinal region以下是10月照的正子攝影報告:正子掃瞄: 【 Indication 】: Right lower lung cancer with hilar encasement s/p target therapy. ˉ 【 Procedure 】: The patient was injected intravenously with 376 MBq of F-18-fluorodeoxyglucose( FDG) after fasting. Blood glucose level was 107 mg/dl at the time of injection. Non-contrast-enhanced CT scan was initially and followed by PET scan obtained from the top of the skull to the knees. CT imaging was performed for attenuation correction and anatomic localization only. ˉ 【 Content 】: 1. There is a focal area (about 1.4cm) of increased uptake of radioactivity in right pulmonary hilar region (SUVmax 10.0). 2. Focal areas of mildly-to-moderately increased uptake in the subpleural consolidations over RLL lung (SUVmax ~3.2). 3. Physiological FDG uptake and accumulation in the brain, tonsils, salivary glands, heart, liver, spleen, GI tracts, GU tracts. 4. No definite abnormal FDG uptake can be demonstrated elsewhere. ˉ 【 Impression 】: 1. An FDG-avid lesion in right pulmonary hilar region, residual tumor or LN metastasis. 2. Moderate FDG-avidity in subpleural consolidations over RLL lung, inflammation is likely.我是今年3月確診為肺腺癌3B,目前在服用安立適治療,請問以下幾個問題:1.請問正子攝影肺門的亮點是原本舊的?
還是新長出來的?
如果是舊的是不是表示症狀沒有改善?
為何還會有亮點?
請問要如何處理?
如果是新長出來的,是不是表示已經抗藥了?
要如何處理?
改其他藥物嗎?
還是化療?
放療?
2.有沒有打顯影劑會影響肺門區的判讀嗎?
3.建議開刀取出主腫瘤和肺門的腫瘤嗎?
如果開刀,會重新化驗嗎?
是全部一起化驗?
還是主腫瘤和肺門分開化驗,化驗就可以知道肺門腫瘤是新長出來?
還是舊的嗎?
4.需要再次做NGS基因檢測嗎?
如果沒做真的抗藥了,會不會以後沒有腫瘤檢體可以化驗?
5.請問醫院開刀取下腫瘤檢體會存放多久?
6.已經做過正子攝影,是不是可以排除腦轉移?
還是要做MRI才能確認?
近期有頭痛和頸部僵硬疼痛,但疼痛程度不需要服用藥物,請問這樣需要照MRI嗎?
還是心理因素造成?
抱歉報告和問題較多,謝謝醫生的回答


小小,40~49歲女性,詢問日期:2022/10/31

楊文達 醫師回覆-胸腔內科


您好:正子攝影報告和電腦斷層差不多, 應該是改善中的右下肺腫瘤和右肺門淋巴結殘餘病灶, 正子攝影可排除腦轉移, 繼續目前治療, 其他後續觀察及計畫可與您的主治醫師詢問!

回覆日期:2022/10/31

彙整補充說明


您好,針對您的問題,我將逐一回答並提供相關的醫學知識。

1. 正子攝影肺門的亮點是舊的還是新長出來的?

正子攝影中肺門區域的亮點可能是舊的病灶或新發病灶。
若是舊的病灶,這表示病情可能沒有改善,因為腫瘤或淋巴結的活性仍然存在。
若是新長出來的病灶,則可能表示腫瘤已經出現抗藥性,這需要進一步的評估。
處理方式可能包括改變目前的治療方案,例如轉用其他靶向藥物、化療或放療,具體需依主治醫師的建議。

2. 顯影劑的使用對肺門區的判讀影響?

使用顯影劑可以提高影像的對比度,幫助醫生更清楚地判讀病變。
若在正子攝影中未使用顯影劑,可能會影響對某些病變的評估,但通常正子攝影的主要目的是評估代謝活性,因此即使未使用顯影劑,仍能提供有用的資訊。

3. 建議開刀取出主腫瘤和肺門的腫瘤嗎?

開刀的決定需考慮多方面因素,包括腫瘤的大小、位置、是否有轉移等。
如果決定手術,通常會對切除的腫瘤進行病理檢查,這可以幫助判斷腫瘤的性質。
若主腫瘤和肺門的腫瘤都被切除,則可以進行統一的病理檢查,這樣能更清楚地了解病灶的狀況。

4. 需要再次做NGS基因檢測嗎?

NGS(下一代基因測序)檢測可以幫助了解腫瘤的基因變異,這對於選擇合適的治療方案非常重要。
如果懷疑腫瘤已經出現抗藥性,進行基因檢測是有必要的。
若未來沒有腫瘤檢體可供檢測,則可能會影響後續的治療決策。

5. 醫院開刀取下腫瘤檢體會存放多久?

通常,腫瘤檢體會在病理檢查後進行保存,保存的時間會依醫院的政策而異,通常可保存數月至數年不等,具體需詢問醫院的病理科。

6. 已經做過正子攝影,是不是可以排除腦轉移?

正子攝影可以提供有關腦部的初步資訊,但若有頭痛或頸部僵硬等症狀,建議還是進行MRI檢查以更精確地評估腦部狀況。
MRI對於腦部病變的檢查更為敏感,能夠更清楚地排除或確認腦轉移的可能性。

最後,對於您提到的頭痛和頸部僵硬,若症狀持續或加重,建議儘早就醫,進一步檢查以排除其他潛在的問題。
希望這些回答能幫助您釐清疑慮,並祝您早日康復!如有其他問題,隨時歡迎詢問。

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