電腦斷層報告分析:從檢查結果看肺癌病變進展與治療效果-胸腔內科

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電腦斷層報告?


以下是今年3月剛確診肺腺癌3B電腦斷層報告(有打顯影劑)Imaging findings: CT of the Chest: The non-enhanced axial and reformatted images are obtained by MDCT. Irregular poor-enhanced mass lesions (~5.8cm @ Se/Im:7/20) (~4.8cm @ Se/Im:3/56) in the right lower lobe with invasion to the right hilum and mediastinum. There are enlarged lymph nodes in the right hilum and mediastinum. Interstitial thickening and ground glass opacity in the right lower lobe of the lung. There is a cystic lesion without significant enhancement in the right kidney. Small hypodense lesions are noted in the liver.Impression: 1) Suspect bronchogenic carcinoma (~5.8cm @ Se/Im:7/20) (~4.8cm @ Se/Im:3/56) in the right lower lobe with invasion to the right hilum and mediastinum. Differential diagnosis: tuberculosis. 2) Suspect metastatic lymphadenopathy in the right hilum and mediastinum. 3) Suspect lymphangetic carcinomatosis in the right lower lobe of the lung. 4) A right renal cyst, Bosniak Classification category I. 5) Small hepatic cysts. ============<< Uniform Cancer Staging Format for Lung Cancer >>============= TNMStage: T4N2M0 (according to AJCC cancer staging 8th ed., 2016) AJCC prognostic stage group: IIIB ================================================================= 1.Imaging date Date of examination (Y/M/D): 2022/03/22 Imaging modality Imaging byCT scan 2.Tumor Location: (TumorLocation) ■Right lower lobe Tumor Size: (TumorSize) Nodule/lesion feature: ■Solid (Se/Im:7/20) ■Size of solid part: 5.8 cm (greatest dimension) 3.Tumor invasion: (TumorCharacteristics & OtherOrganInvasion) ■Invades hilar fat ■Separate tumor nodule(s) in the same lobe as the primary ■Invades mediastinum or mediastinal fat 4.Regional nodal metastasis: (LymphNode) ■Suspicious nodal metastatic location(s): ■ipsilateral hilar ■ipsilateral mediastinal 5.Distant metastasis: (MetastaticOrgan) ■No distant metastasis以下是6月電腦斷層報告(沒有打顯影劑)CT of chest without contrast enhancement shows: Techniques: From lower neck to the renal level in 3-mm contiguous section for non-enhanced CT studyCoronal (3mm) and sagittal (5mm) reconstruction performedImaging findings: Some small lymph nodes at left supraclavicular region Regressive change of subpleural consolidation in the upper RLL as compared with last imagesObvious regression of the RLL cavitary lesion Ground glass opacity in the medial RLLInfiltration and atelectasis in the RLLStable 4mm nodule in the LLLRegressive change of the enlarged right hilar and mediastinal LN sas compared with last imagesNo definite pneumothorax or pleural effusion No definite pericardial effusion or pneumopericardium A rightrenal cyst No obvious adrenal mass found No definite enlarged lymph nodes noted in the upper retroperitoneum Some small but visible lymph nodes at the upper retroperitoneum Impression: * Some small lymph nodes at left supraclavicular region * Regressive change of subpleural consolidation in the upper RLLas compared with last images* Obvious regression of the RLL cavitary lesion * Ground glass opacity in the medial RLL* Stable 4mm nodule in the LLL* Regressive change of the enlarged right hilar and mediastinal LN以下是9月照的胸部電腦斷層報告(有打顯影劑):Computed Tomography of Chest With and Without Enhancement Shows:Techniques: From lower neck to liver level in 3-mm section for non-contrast CTFrom lower neck to liver level in 3-mm section for contrast CTCoronal (3mm) and sagittal (5mm) reconstructions are also doneThis study has been compared to previous CT study on 20220617Findings:Partial regressive change of subpleural consolidation in the upper RLL as compared with last imagesPartial regressive change of ground glass opacity in the medial RLLStable 4mm nodule in the LLLStable small lymph nodes at left supraclavicular, right hilar and mediastinal regionSome small but visible lymph nodes at the upper retroperitoneum Stable right renal cyst Hypodense lesions without enhancement in right lobe liver, may be cysts No definite pneumothorax.No definite pleural effusion.No definite pericardial effusion.Patent main pulmonary trunk and branches, no obvious thrombus noted.No definite of double lumen, intimal flap or medial displacement of aorta wall suggesting aortic dissection.No definite adrenal mass.No definite hydronephrosis.No definite bone destruction.Kindly note that subtle mucosal lesion could not be well evaluated on routine CTIMP:* Partial regressive change of subpleural consolidation in the upper RLL as compared with last images* Partial regressive change of ground glass opacity in the medial RLL* Stable 4mm nodule in the LLL* Stable small lymph nodes at left supraclavicular, right hilar and mediastinal region以下是10月照的正子攝影報告:正子掃瞄: 【 Indication 】: Right lower lung cancer with hilar encasement s/p target therapy. ˉ 【 Procedure 】: The patient was injected intravenously with 376 MBq of F-18-fluorodeoxyglucose( FDG) after fasting. Blood glucose level was 107 mg/dl at the time of injection. Non-contrast-enhanced CT scan was initially and followed by PET scan obtained from the top of the skull to the knees. CT imaging was performed for attenuation correction and anatomic localization only. ˉ 【 Content 】: 1. There is a focal area (about 1.4cm) of increased uptake of radioactivity in right pulmonary hilar region (SUVmax 10.0). 2. Focal areas of mildly-to-moderately increased uptake in the subpleural consolidations over RLL lung (SUVmax ~3.2). 3. Physiological FDG uptake and accumulation in the brain, tonsils, salivary glands, heart, liver, spleen, GI tracts, GU tracts. 4. No definite abnormal FDG uptake can be demonstrated elsewhere. ˉ 【 Impression 】: 1. An FDG-avid lesion in right pulmonary hilar region, residual tumor or LN metastasis. 2. Moderate FDG-avidity in subpleural consolidations over RLL lung, inflammation is likely.我是今年3月確診為肺腺癌3B,目前在服用安立適治療,請問以下幾個問題:1.之前沒有照過正子攝影,這次是第1次照正子攝影,請問正子攝影報告上的肺門有亮點,請問是舊的腫瘤癌細胞產生?
還是新長的腫瘤癌細胞?
如果是舊的,請問為何正子會有亮點?
亮點代表?
如果是新的腫瘤癌細胞,是不是代表已經抗藥?
惡化?
轉移了?
2.近期有頭痛情況(不是到是不是心理因素),也不是很痛,就是不舒服,只有睡眠品質較差頭痛情況會較嚴重,沒有嘔吐,就單純只有頭痛,請問10月剛照正子攝影,是不是可以排除腦轉移?
還需要再照腦部MRI嗎?
請問腦轉移症狀?
頭痛情況是如何疼痛?
劇烈疼痛嗎?
有哪個時間點會較嚴重嗎?
抱歉問題較多,謝謝醫生的回答


小可,40~49歲女性,詢問日期:2022/10/25

黃伊文 醫師回覆-胸腔內科


Dear 小可: 肺門 縱膈腔 淋巴 3 月電腦斷層就有 所以後來的正子攝影應該是舊的正子攝影亮起來因部位不同有不一樣解讀 不夠基本上是代表有癌細胞看起來非新的 所以應該沒有惡化腦部轉移用正子確實比較有缺點 建議再照一次腦部MRI確保狀況腦轉移無法特別用臨床症狀來區分彰化醫院關心您

回覆日期:2022/10/25

彙整補充說明


根據您提供的電腦斷層報告和正子攝影結果,我們可以對肺癌的病變進展及治療效果進行分析。

首先,您在3月的CT報告顯示,右下肺有不規則的腫塊,大小約5.8公分,並且有侵犯到肺門和縱膈的情況,這表明腫瘤的侵襲性較強,並且有淋巴結腫大,這些都是肺癌進展的指標。
根據TNM分期,您的病情被評估為T4N2M0,屬於III期,這意味著腫瘤已經擴散到周圍的淋巴結,但尚未有遠端轉移。

隨後在6月和9月的CT檢查中,您提到有明顯的回歸變化,尤其是右下肺的腔隙病變和小結節的穩定,這顯示出治療可能有一定的效果。
這些回歸變化通常是指腫瘤的縮小或穩定,這是治療成功的正面指標。

至於10月的正子攝影報告,顯示右肺門區域有放射性物質的聚集,SUVmax為10.0,這可能表示殘留的腫瘤或淋巴結轉移。
這裡的亮點可能是舊的腫瘤細胞所產生的,也可能是新的腫瘤細胞。
亮點的出現通常意味著該區域有活躍的代謝活動,這在癌症中是常見的現象。
如果是新的腫瘤細胞,則可能意味著病情的惡化或抗藥性,但這需要結合臨床症狀和其他檢查結果來進一步確認。

關於您的頭痛問題,頭痛的性質和頻率是重要的指標。
腦轉移的症狀通常包括持續性頭痛、視力變化、癲癇發作等。
如果您的頭痛只是偶爾出現且不劇烈,且在最近的MRI檢查中未見異常,則可以相對排除腦轉移的可能性。
然而,若頭痛持續或加劇,建議您進一步進行MRI檢查,以確保沒有潛在的問題。

最後,關於是否需要手術,這取決於多個因素,包括腫瘤的大小、位置、是否有淋巴結轉移以及您的整體健康狀況。
由於您目前正在接受安立治療,建議與主治醫師討論最佳的治療方案,可能包括持續的藥物治療、放療或手術等選項。

總結來說,您的病情在治療後顯示出一定的改善,但仍需密切監測。
建議您定期回診,並與醫療團隊保持良好的溝通,以便及時調整治療計劃。
希望您能夠早日康復!

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